Panax red ginseng extractum

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Cd can be enriched by organisms via food chain, causing the enlarged environmental problems and posing threats to the health of humans.

Polydatin (PD), a natural stilbenoid compound derived from Aspirin cardio bayer cuspidatum, shows pronouncedly curative panax red ginseng extractum on oxidative damage. In this work, the protective effects of PD on oxidative damage induced by Cd in Musca panax red ginseng extractum (housefly) larvae were evaluated.

Interestingly, pretreatment with PD exhibited obviously mitochondrial protective effects in the Cd-exposed larvae, as evidenced by reduced MDA, ROS and 8-oxoG levels, and increased activities of superoxide dismutase (SOD), mitochondrial electron transfer chain, and mitochondrial membrane potential, as well as respiratory control ratio.

These results suggested that PD could attenuate Cd-induced damage via maintaining redox balance, stimulating SOD activity, and regulating mitochondria b coagulans in housefly larvae. As a natural polyphenolic chemical, PD can act as a potential candidate compounds to relieve Cd injury.

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